IC50 without Preincubation | IC50 with Preincubation | |||||||
---|---|---|---|---|---|---|---|---|
Antagonists | PKR1 | PKR2 | PKR1 | PKR2 | ||||
PK1 | PK2 | PK1 | PK2 | PK1 | PK2 | PK1 | PK2 | |
nM | nM | |||||||
MetPK1 | 27 ± 4.54 | 98 ± 4.4 | 36.4 ± 4.56 | 42.7 ± 3.52 | 10.2 ± 4.63 | 29.98 ± 6.66 | 3.6 ± 1.29 | 4.49 ± 0.54 |
(2.6) | (3.3) | (10.1) | (9.5) | |||||
A1MPK1 | 27.6 ± 5.03 | 208 ± 83.75 | 40.7 ± 6.5 | 116 ± 91.53 | 16.1 ± 2.89 | 32.8 ± 2.6 | 8.2 ± 2.61 | 7.9 ± 5.59 |
(1.7) | (6.3) | (5.0) | (14.7) |