TABLE 2

Kinetics of interaction of gemcitabine with CNT1-reference and its four common protein altering variants Vaccinia-infected HeLa cells were transfected with CNT1 and its variants as described under Materials and Methods. The uptake of [³H]thymidine in the presence of increasing concentrations of gemcitabine was measured after a 4-min incubation. Data represent mean ± S.E. from at least three different experiments.