[3H]MRE 3008F20 Binding | |||
---|---|---|---|
Compounds | KH, KL | Ki + GTP | RH |
nM | |||
Cl-IB-MECA | 0.80 ± 0.1 | 28 ± 3 | |
67 ± 6 | 75 ± 7 | ||
NECA | 18 ± 3 | 24 ± 2 | |
1250 ± 250 | 1300 ± 200 | ||
R-PIA | 38 ± 6 | 26 ± 3 | |
2100 ± 250 | 2200 ± 280 | ||
S-PIA | 260 ± 29 | 24 ± 3 | |
19,000 ± 2500 | 21,000 ± 2800 | ||
MRE 3008F20 | 2.0 ± 0.3 | 1.8 ± 0.2 | |
MRE 3105F20 | 1.7 ± 0.2 | 1.6 ± 0.1 | |
CGS 15943 | 78 ± 6 | 85 ± 8 | |
DPCPX | 850 ± 90 | 920 ± 97 | |
SCH 58261 | >10,000 | >10,000 |