Summary of the IC50 values for the effect of PABA/NO on NIH3T3 cells transfected with GSTπ, γGCS, MRP1, or appropriate combinations compared with sham-transfected parental cells (3T3/pc)
Data are represented as means ± S.D. of three independent experiments.
| IC50 | Ratio | |
|---|---|---|
| 3T3/pc | 11 ± 1.5 | 1.0 |
| 3T3/GCS | 16 ± 3.6 | 1.5 |
| 3T3/GST | 10 ± 1.6 | 0.9 |
| 3T3/GCS/GST | 19 ± 2.1 | 1.7 |
| 3T3/MRP | 51 ± 6.5 | 4.6 |
| 3T3/MRP/GCS | 22 ± 1.3 | 2.0 |
| 3T3/MRP/GST | 39 ± 3.0 | 3.5 |
| 3T3/MRP/GCS/GST | 46 ± 6.3 | 4.2 |