AUIC comparison of various therapeutic situations
| Inhibitor Type | Maximum Concentration or Activity (% Inhibition) | Binding Affinity | AUIC |
|---|---|---|---|
| nM | % | ||
| A | 50 (nM) | 6.8a | 22.5 |
| 150 (nM) | 6.8 | 40.3 | |
| 50 (nM) | 0.68 | 67.6 | |
| B | 50 (nM) | 1a | 20.1 |
| 150 (nM) | 1 | 44.7 | |
| 50 (nM) | 0.1 | 48.2 | |
| Bortezomib | 60 (%) | N/A | 19.6 |
| 100 (%) | N/A | 39.9 |
↵ a These values are from the original assumption about binding affinities of inhibitor A and B.