TABLE 1

IC50 values for growth inhibition

Cell Line Copper Copper Resistance Ratioa DDP DDP Resistance Ratioa CBDCA CBDCA Resistance Ratioal-OHP l-OHP Resistance Ratioa
μM μM μM μM
Me32a 61.9 6.2 9.1 24.5
MeMNK 485.0 7.8 8.8 1.4 68.2 7.5 7.5 0.3
MeWND 642.6 10.4 13.3 2.1 —b —b 8.1 0.3

  • ↵ a Relative to the IC50 for Me32a cells.

  • ↵ b Undeterminable because of a minimal cell kill up to 50 μM.