TABLE 1

E_max and EC₅₀ values of agonist-stimulated [³⁵S]GTPγS binding in cerebellum Data are mean values ± S.E.M. obtained from nonlinear regression analyses of the data shown in Figs. 3 and 4.

Drug	Treatment	E_max	EC₅₀
		% of stimulation	nM
WIN 55,212-2	Vehicle	230 ± 6.3	83 ± 15
	THC	187 ± 21	167 ± 21^*
CP 55,940	Vehicle	193 ± 5.1	8.5 ± 0.8
	THC	130 ± 18^*	15 ± 1.0^**
PIA	Vehicle	255 ± 13	90 ± 16
	THC	249 ± 10	113 ± 20
Baclofen	Vehicle	233 ± 19	7615 ± 357
	THC	251 ± 18	8140 ± 1012

↵* , p < 0.05
↵** , p < 0.01 different from vehicle-treated mice