Drug | Treatment | Emax | EC50 |
---|---|---|---|
% of inhibition | nM | ||
WIN 55,212-2 | Vehicle | 33 ± 2.0 | 1432 ± 386 |
THC | 32 ± 4.1 | 2705 ± 254* | |
CP 55,940 | Vehicle | 38 ± 1.6 | 44 ± 17 |
THC | 30 ± 1.4* | 112 ± 43 | |
THC | Vehicle | 24 ± 3.3 | 654 ± 228 |
THC | 14 ± 1.4* | 797 ± 290 | |
PIA | Vehicle | 48 ± 2.6 | 141 ± 19 |
THC | 39 ± 2.6* | 147 ± 28 | |
Baclofen | Vehicle | 49 ± 2.6 | 2978 ± 818 |
THC | 40 ± 1.8* | 5361 ± 613 |
↵* , p < 0.05; different from vehicle-treated mice