TABLE 1
K
i
values of KYT-1 and KYT-36 toward gingipains and other proteinases
Proteinase
K
i
KYT-1
KYT-36
M
Rgp
1.3×10
−10
>10
−4
Kgp
2.6× 10
−6
7.5×10
−11
Trypsin
1.2× 10
−6
1.3× 10
−7
Cathepsin B
3.4× 10
−8
3.7× 10
−9
Cathepsin L
1.2× 10
−8
7.0× 10
−8
Cathepsin H
1.5× 10
−4
1.6× 10
−4