Distinct pharmacology of PAR-2 polymorphic variants A summary of the distinct pharmacological properties of the human polymorphic variants of PAR-2, derived from studies by Compton et al. (2000) that are described further in the text.
| PAR-2-Phe240 | PAR-2-Ser240 | |
|---|---|---|
| Allele frequency | 0.916 | 0.084 |
| Activating protease | Trypsin | |
| tc-LIGRLO | ||
| Peptide agonist | SLIGRL | TLIGRL |
| SLIGKV | SFLLRN | |
| SFLLRN | TFLLR | |
| tc-YGPKF |