Effect of ATRA on the Binding of Nucleolin to Bcl-2 ARE-1 RNA Results are expressed as mean femtomoles of 32P-ARE-1 RNA ± S.E. co-immunoprecipitated with either mouse IgG or anti-nucleolin monoclonal antibody. Combined results of three experiments with three observations per experiment.
| Control/IgG | 0.9 ± 0.3 |
| Control/Nucleolin Ab | 13.7 ± 4.0* |
| ATRA/IgG | 1.0 ± 0.4 |
| ATRA/Nucleolin Ab | 2.1 ± 0.5 |
↵* P < 0.02 compared with ATRA/ Nucleolin Ab group, one-tailed t test