Comparison of parameters for GABA dose-responses determined in Ringer's solution and in various picrotoxin concentrations
| Ringer's | 10 μM PTX | 100 μM PTX | ||||||
|---|---|---|---|---|---|---|---|---|
| EC50 | nH | EC50 | nH | Rmax | EC50 | nH | Rmax | |
| μM | μM | μM | ||||||
| Measured | 0.99 ± 0.06 | 2.17 ± 0.29 | 8.1 ± 0.16 | 2.1 ± 0.08 | 0.76 ± 0.01 | 18.1 ± 4.4 | 1.4 ± 0.40 | 0.42 ± 0.04 |
| Model | 0.98 ± 0.02 | 2.18 ± 0.13 | 3.21 ± 0.04 | 1.67 ± 0.03 | 0.76 ± 0.01 | 5.8 ± 0.1 | 1.47 ± 0.04 | 0.29 ± 0.01 |