TABLE 6

Summary of clone information

Clone 23 113
Gene Name RSK4, also named RPS6KA 6PAK5, also named PAK7
Localization Chromosome X 1. intron Chromosome 20 3. introna,
    site a, ChIP-confirmed, EMSA binding
    Site b, ChIP-confirmed, EMSA binding
Swiss-Prot/mRNA NCBI Q9UK32/NM_014496 Q9P286/NM_045653
Reference Yntema et al., 1999; Kohn et al., 2003Pandey et al., 2002; Dan et al., 2002
mRNA Expression Caco-2 cells, human liver, human brain, rat liver, rat brain, rat kidney human liver, human brain, rat liver, rat brain, rat kidney
HNF4α Promoter Binding Sites -1430 (prosite a), ChIP-confirmed, EMSA binding -951 (prosite a), ChIP-confirmed, EMSA no binding
-2053 (prosite b), ChIP-confirmed, EMSA binding
-1766 (prosite b), EMSA binding
-2181 (prosite c), ChIP-confirmed, EMSA no binding
Molecular Function Protein kinase activity Protein kinase activity
Biological Process Cell communication/signal transduction Cell communication/signal transduction
  • a Coincides with the 1. intron behind the 1. translated exon.