TABLE 1

1-CBI—induced inhibition of in vivo SV40 virus production: viral plaque assay

BSC-1 cells were infected with 1-CBI—pretreated SV40 virions as described under Materials and Methods. Cells were stained with Neutral red, and viral plaques were counted on postinfection day 9. Total plaque numbers are expressed as mean percentages of total control plaque numbers (100% = 1.9 × 10⁷ pfu/ml). Plaque-forming units were calculated as follows: (total number of plaques) × (SV40 virion dilution factor)/(infection volume).