Cross-resistance to drugs in HeLa and HR3 cells
IC50 data are expressed ± S.E. (n = 5); values were calculated from the cytotoxicity curves.
| HeLa | HR3 | Fold resistance | |
|---|---|---|---|
| M | |||
| Cisplatin | (5.5 ± 0.4)×10−8 | (9.9 ± 1) ×10−7 | 18 |
| Mitomycin C | (9 ± 1) ×10−8 | (9 ± 0.8) ×10−7 | 10 |
| Ethyl methane-sulfonate | (8 ± 0.9) ×10−3 | (2.4 ± 0.3)×10−2 | 5 |
| Colchicine | (3 ± 0.2) ×10−8 | (4 ± 0.7) ×10−8 | 1.3 |
| Adriamycin | (1.5 ± 0.2) ×10−6 | (1.5 ± 0.2)×10−6 | 1 |