Equilibrium dissociation constants for antagonist-CCR5 receptor complexes as measured by displacement or modification of 125I-MIP-1α binding
| Ligand | KB (95% Confidence Limits) |
|---|---|
| nM | |
| MIP-1α | 8.0 ± 1.2 (4.7-11.2) |
| TAK779 | 15.8 (7.9-31.6) |
| Sch-C | 6.3 (4-10) |
| Sch-D | 4.0 (2.5-6.3) |
| UK-427,857 | 2.0 (1.2-3.1) |
| 873140 | 2.5 (1.6-3.2) |