TABLE 4
Characterization of mutant HIV-1 strains
p24 indicates amount of HIV-1 p24 antigen in the virus stocks prepared from the supernatants of (mutant) virus-infected CEM cell cultures. Viral load is the number of RNA copies present in the virus stocks as determined by a signal amplification nucleic acid probe assay (VERSANT HIV-1 RNA 3.0 Assay). Infectivity factor that is required to dilute the virus stocks to obtain equal (100%) infectivity of the cell cultures as quantified by the number of CCID50. Relative infectivity is calculated relative to wild-type virus.