Gene/mRNA | Mean -Fold Change | Cellular Roles | |
---|---|---|---|
G14α | Range | ||
G14α regulated | |||
Up-regulated genesa | |||
Heparin binding EGF-like growth factor (proHB-EGF) | 3.4 | 2.5-4.4 | Transmembrane precursor of HB-EGF |
Leukemia inhibitory factor (Lif) | 2.8 | 2.2-3.5 | Neuropoietic cytokine |
Ectonucleotide pyrophosphatase/phosphodiesterase 1 (Enpp1) | 2.7 | 2.5-2.8 | Membrane protein, conversion of nucleotides |
ATP-binding cassette transport protein (Abcb1a; Mdr1) | 2.5 | 2.1-3.0 | Xenobiotic membrane transporter |
A kinase (PRKA) anchor protein (gravin) 12 (Akap12) | 2.4 | 2.3-2.5 | Kinase scaffolding protein |
FMS-like tyrosine kinase (Flt1) | 2.4 | 2.3-2.5 | Receptor for VEGF-A, placental GF |
Potassium channel K6 (TWIK-2; Kcnk6) | 2.3 | 2.1-2.5 | Outward rectifying potassium channel |
Core promoter element binding protein (Copeb) | 2.3 | 2.1-2.5 | Transcriptional activator |
LIM domain-containing; Enigma homolog (Enh) | 2.2 | 2.1-2.4 | PKC binding scaffolding protein |
Down-regulated genesb | |||
Xanthine dehydrogenase (Xdh) | -2.8 | -2.2,-3.5 | Converts xanthine to urate |
C-CAM4 | -2.7 | -2.0,-3.3 | Cell-cell adhesion molecule |
Fc receptor, IgG, low affinity III (FcgammaR3a) | -2.6 | -2.1,-3.0 | Immune complex receptors |
Leucine arylaminopeptidase (Lap1; Anpep) | -2.6 | -2.6,-2.7 | Aminopeptidase for modification of MHCII molecules |
G15α | |||
Up-regulated genesc | |||
Arg/Abl-interacting protein (ArgBP2) | 3.5 | 2.5-4.4 | Adaptor protein, signaling mediator |
NADH/NADPH mitogenic oxidase subunit p65-mox (Nox1) | 2.9 | 2.4-3.3 | NADPH oxidases, superoxide generating |
Ceruloplasmin (Cp; CERP) | 2.6 | 2.5-2.7 | Copper-binding serum protein |
cAMP-reg. guanine nucleotide exchange factor (Epac2) | 2.5 | 2.4-2.7 | cAMP-binding protein, modulates monomeric GTPases |
Exodus/MIP-3 alpha/LARC; CC chemokine ST38 | 2.4 | 2.3-2.5 | Chemokine |
CDP-diacylglycerol synthase (Cds1) | 2.3 | 2.2-2.5 | Involved in phosphatidylinositol metabolism |
Lymphotactin; small inducible cytokine, C1 (Scyc1) | 2.3 | 2.3-2.3 | Chemotactic chemokine |
AMP-activated protein kinase (Prkaa2) | 2.2 | 2.1-2.2 | Rate limiting enzyme in malonyl-CoA synthesis |
Down-regulated genesd | |||
No annotated genes (of 2 total) |
↵ a List includes all defined annotated genes (nine) of 45 total that increased.
↵ b List includes all defined annotated genes (four) of 25 total that decreased.
↵ c List includes all defined annotated genes (eight) of 16 total that increased.
↵ d List includes all defined annotated genes (zero) of two total that decreased.