Rate constants for wild-type and mutant channels
| Channel | kon | koff | Kd |
|---|---|---|---|
| μM−1s−1 | s −1 | μM | |
| Kv3.1 WT | 1.4 ± 0.1 | 39.8 ± 5.3 | 28.8 ± 3.6 |
| Kv3.1 L422I | 0.37 ± 0.05 | 73.2 ± 4.5 | 202.7 ± 11.7 |
| Kv1.5 WT | 0.30 ± 0.02 | 60.0 ± 5.5 | 210.8 ± 5.9 |
| Kv1.5 I502L | 1.1 ± 0.3 | 36.7 ± 1.6 | 35.4 ± 1.9 |