Receptor | Kd | Bmax | n |
---|---|---|---|
nM | fmol / 104 cells | ||
Wild-type CB2 | 1.2 ± 0.4 | 3.8 ± 1.3 | 8 |
C1.55(40)S | N.D. | 2 | |
C2.59(89)S | 4.3 ± 0.9 | 5.1 ± 1.7 | 6 |
C4.66(174)A | N.D. | 3 | |
C175A | N.D. | 3 | |
C179A | N.D. | 3 | |
C6.47(257)S | 8.4 ± 4.0 | 6.2 ± 2.1 | 4 |
C7.38(284)S | 4.2 ± 1.0 | 4.3 ± 1.4 | 5 |
C7.42(288)S | 1.1 ± 0.5 | 2.0 ± 1.7 | 4 |
C284S/C288S | 1.6 ± 0.9 | 5.1 ± 3.7 | 4 |
C89S/C257S/C284S/C288S | N.D. | 3 |
N.D., no detectable binding.