TABLE 6

FMO3 upstream genetic variation—population-specific allelic frequencies

	Variant Allelic Frequency (95% CI)
SNP	Hispanic American (n = 402)	African American (n = 402)	White (n = 400)
−2650C>G	0.438 (0.388, 0.488)^a^b	0.259 (0.216, 0.305)^c	0.303 (0.258, 0.350)^c
−2589C>T	0.007 (0.000, 0.016)^b	0.007 (0.000, 0.016)^b	0.040 (0.023, 0.064)^a^c
−2543T>A	0.291 (0.247, 0.338)^a^b	0.192 (0.155, 0.234)^c	0.205 (0.167, 0.248)^c
−2177G>C	0.286 (0.243, 0.334)^a^b	0.124 (0.094, 0.161)^b^c	0.068 (0.045, 0.097)^a^c
−2106G>A	0.012 (0.002, 0.023)^b	0.027 (0.014, 0.048)	0.040 (0.023, 0.064)^c
−2099A>G	0.000 (0.000, 0.000)	0.000 (0.000, 0.000)	0.000 (0.000, 0.000)
−1961T>C	0.012 (0.002, 0.023)	0.020 (0.009, 0.039)	0.005 (0.000, 0.012)

↵ a Different from African American study population, P < 0.016 (Fisher's exact test, Bonferroni adjustment).
↵ b Different from White study population, P < 0.016 (Fisher's exact test, Bonferroni adjustment).
↵ c Different from Hispanic American study population, P < 0.016 (Fisher's exact test, Bonferroni adjustment).