Sodium channel activation in cells modified by capsaicin or capsazepine
Results are given as mean ± S.E. of changes in individual cells.
| Vact/mV | Sact/mV | Erev/mV | |
|---|---|---|---|
| Timed controls (n = 3) | −1.5 ± 0.8 | 0.3 ± 0.6 | 3.0 ± 3.4 |
| 30 μM Capsaicin (n = 4) | −1.4 ± 1.7 | 0.8 ± 0.7 | 1.8 ± 2.5 |
| 100 μM Capsaicin (n = 4) | 4.0 ± 1.0* | 2.1 ± 0.7 | −2.7 ± 9.6 |
| 30 μM Capsazepine (n = 3) | 1.5 ± 1.4 | 0.0 ± 0.2 | 1.6 ± 4.6 |
↵* Significantly different from the change in timed control cells; P < 0.05.