Heterologous expression of RDL alone or with other putative insect GABAR subunits results in receptors with distinct pharmacologies
| Subunit combination | Heterologous Expression | Pharmacology | Reference |
|---|---|---|---|
| RDL homomer | Oocytes, S2 cells (anion channel) | Picrotoxinin-sensitive; Bicuculline-insensitive | Hosie and Sattelle, 1996a |
| RDL + LCCH3 | Sf-9 | Picrotoxinin-insensitive; Bicuculline-sensitive | Zhang et al., 1995 |
| RDL + GRD | Not reported | Not reported | N/A |
| GRD + LCCH3 | Oocytes (cation channel) | Picrotoxinin-sensitive; Bicuculline-insensitive | Gisselmann et al., 2004 |