TABLE 3

[3H]DA uptake in WT and α4(-/-) mice Vmax is defined as the maximal rate of [3H]DA uptake under the present experimental conditions.**, p ≤ 0.01, significantly different from WT values, unpaired t test.

KmVmax
nM fmol/mg protein/min
WT 174.3 ± 15.6 3083.7 ± 188.5
α4 (–/–) 292.8 ± 19.3** 3058.0 ± 114.4