Model parameters The model is fit to the measured GI50 concentration of 60 cell lines using the RT-PCR-measured relative gene expression of seven genes in these same cell lines. Thus, the fitting procedure used 420 data points using 14 parameters to describe the 60 possible outcomes.
| ANXA1 | KRT8 | XBP1 | TRA1 | AXL1 | IGFBP7 | CDH1 | |
|---|---|---|---|---|---|---|---|
| c t | +1.04 | –0.10 | –0.45 | –1.19 | +0.02 | –0.46 | –0.37 |
| d t | +0.12 | –0.17 | +0.69 | +0.37 | –0.06 | –0.45 | –0.22 |