Effect of nicotinic agonists on intracellular calcium in β -TC6 cells Efficacy relative to nicotine was set equal to 100.
| Nicotinic Agonists | EC50 | Efficacy |
|---|---|---|
| μM | ||
| (−)-Nicotine | 20 ± 5 (n = 4) | 100 |
| (±)-Epibatidine | 0.020 ± 0.030 (n = 6) | 95 ± 21 |
| (−)-Cytisine | 22 ± 7 (n = 3) | 61 ± 17 |
| DMPP | 15 ± 2 (n = 5) | 48 ± 9 |
| A-85380 | 20 ± 8 (n = 4) | 86 ± 23 |