Dose-response curves properties for BeKm-1-induced blockade at −70 mV (see Fig. 4, right)
Ins is the fractional amount of toxin-insensitive ERG current, N is the number of experiments (Kd values in parenthesis derive from on-kinetics experiments).
| Ins | Kd | N | |
|---|---|---|---|
| nM | |||
| Human | |||
| ERG1 | |||
| ERG2 | 0.025 | 7.7 ± 0.6 | 8 |
| ERG3 | 0.1 | 77 ± 16 | 5 |
| Rat | 0.06 | 11.5 ± 1.1 | 6 |
| ERG1 | 0.12 | 19 ± 1.6 | 6 |
| ERG2 | 0 | 4.2 ± 0.5 (1.51 ± 0.12) | 5 |
| ERG3 | 0.25 | 747 ± 58 | 6 |