Parameter values obtained fitting the data of the agonist estradiol binding to the estrogen receptors, shown in Fig. 6, to the two-state dimer receptor model Data were obtained from Fig. 2 in Notides et al. (1981). Data are presented as mean ± S.E.M. values given by the regression program (GRAFIT).
| Parameter | Value |
|---|---|
| R T a | 2.44 ± 0.05 pmol/mg protein |
| C1 | 0.178 ± 0.010 nM |
| C2 | 0.42 ± 0.04 nM2 |
| [A]50 | 0.642 nM |
↵ a Maximum binding = 2 × RT = 4.89 pmol/mg protein