TABLE 1

Characterization of the original TCC

T-cell receptor nomenclature according to Lefranc (2001). This nomenclature defines the TRAV (5*01) and TRBV (5-4*04) families, each of which contain many subfamilies (5*01).

TCC Specificity Cross-Reactivity TRAV Expression TRBV Expression Transfectants
RuBa1a PFX NRFX 5*01 5-4*04 T1.84
RuBa2a CPFX 26-1*01 20-1*02 T2.18
RuBa11a CPFX NRFX 8-4*01 19*01 T11.1
UNO2b SMX SMT, STH, SPD, SMP, SID, SDM, SDX 3*01 2*01 T25
UNO3b SMX 3*01 25-1*01 T327
H13c SMX SPD 9-2*02 5-1*01 T13
  • TRAV, T-cell receptor α gene for the variable region; TRBV, T-cell receptor β gene for the variable region.

  • a TCC described in Schmid et al. (2006).

  • b TCC described in Depta et al. (2004).

  • c TCC described in von Greyerz et al. (2001).