Ligand | M1 mAChR | M4 mAChR | ||
---|---|---|---|---|
LogKB | Logα | LogKB | Logα | |
[3H]NMS | ||||
WIN 51,708 | −6.01 ± 0.12 | −0.23 ± 0.01*† (0.59) | −6.34 ± 0.21* | 0.68 ± 0.15*† (4.77) |
WIN 62,577 | −5.38 ± 0.35 | −0.75 ± 0.05* (0.18) | −5.41 ± 0.31* | −0.14 ± 0.04* (0.73) |
[3H]QNB | ||||
WIN 51,708 | −5.98 ± 0.04*† | −0.15 ± 0.01*† (0.71) | −6.29 ± 0.26*† | −0.38 ± 0.01*† (0.42) |
WIN 62,577 | −5.35 ± 0.05*† | −0.39 ± 0.01*† (0.40) | −5.60 ± 0.05*† | −0.60 ± 0.01*† (0.25) |