Accumulation of copper, DDP, CBDCA, and L-OHP in CTR1-/- cells as a percentage of that in CTR1+/+ cells
Data are presented as mean ± S.E.M.
Drug & Concentration | Comparative Cell Accumulation | p Value |
|---|---|---|
| % | ||
| 64Cu | ||
| 2 μM | 5.7 ± 2.0 | 1.36 × 10−10 |
| DDP | ||
| 2 μM | 36.3 ± 9.7 | 0.007 |
| 10 μM | 30.0 ± 1.7 | 0.00025 |
| CBDCA | ||
| 2 μM | 35.1 ± 5.5 | 0.00008 |
| 10 μM | 49.5 ± 19.3 | 0.017 |
| 12 μM | 45.6 ± 19.0 | 0.0033 |
| L-OHP | ||
| 2 μM | 36.3 ± 9.7 | 0.007 |
| 6 μM | 84.9 ± 9.0 | 0.148 |
| 10 μM | 110.6 ± 14.6 | 0.427 |