Plasma biochemical parameters of Y5 antagonist-treated or pair-fed DIO mice
Data are means ± S.E.M. (n = 9-11 mice).
Vehicle | Y5 Antagonist | Pair-Fed | |
|---|---|---|---|
| TC (mg/dl) | 156.1 ± 6.4 | 116.7 ± 7.8** | 136.9 ± 7.8 |
| HDL-C (mg/dl) | 123.0 ± 4.1 | 104.1 ± 6.6 | 110.4 ± 6.0 |
| Non-HDL-C (mg/dl) | 24.2 ± 2.0 | 12.2 ± 1.2**# | 19.1 ± 1.4 |
| TG (mg/dl) | 20.4 ± 1.3 | 25.7 ± 2.1 | 22.7 ± 1.9 |
| FFA (μEq/l) | 412.6 ± 23.2 | 456.2 ± 31.4 | 450.9 ± 19.1 |
| Glucose (mg/dl) | 205.5 ± 7.1 | 186.8 ± 10.9 | 195.8 ± 4.6 |
| Insulin (ng/ml) | 5.07 ± 0.50 | 1.74 ± 0.19**## | 4.00 ± 0.37 |
| Leptin (ng/ml) | 45.58 ± 2.63 | 19.25 ± 3.73**## | 38.07 ± 3.36 |
| T3 (ng/ml) | 0.74 ± 0.03 | 0.67 ± 0.04 | 0.63 ± 0.03* |
| T4 (μg/dl) | 4.43 ± 0.17 | 2.02 ± 0.10**## | 4.15 ± 0.12 |
*p < 0.05, **p < 0.01 vs. ad libitum-fed vehicle-treated group.
↵## p < 0.01 vs. pair-fed vehicle-treated group.