TABLE 2

Inhibition of [3H]DPCPX, [3H]ZM 241385, [3H]MRE 2029F20, and [3H]MRE 3008F20 binding by caffeine at A1, A2A, A2B, and A3 adenosine receptors expressed in human HT29 cells, respectively

Data are expressed as the mean ± S.E.M. Ki value represents the concentration of drug able to displace 50% of the radioligand.

[3H]DPCPX [3H]ZM 241385 [3H]MRE 2029F20 [3H]MRE 3008F20
μM
Caffeine Ki 45 ± 5 18 ± 3 10 ± 1 13 ± 2