Predicted secondary AHR protein structures of transactivation domains in different species and strains.
Protein | Dioxin LD 50 (male) | α-Helix | Random Coil | Ambiguous States | Extended Strand |
|---|---|---|---|---|---|
| μg/kg | % | % | % | % | |
| Rat | |||||
| L-E WT | 18 | 19.1 | 74.0 | 1.59 | 5.4 |
| H/W | >9600 | ||||
| IV | 19.9 | 72.2 | 0.36 | 7.6 | |
| DV | 18.4 | 74.3 | 1.47 | 5.9 | |
| Mouse | |||||
| C57BL/6 (Ahrb1) | 128 | 19.6 | 70.9 | 1.11 | 8.49 |
| DBA/2J (Ahrd) | 2600 | 19.4 | 73.3 | 0.64 | 6.7 |
| Guinea Pig | 1–2 | 15.2 | 76.1 | 2.27 | 6.5 |
| Hamster | 3000–5000 | 33.2 | 62.6 | 0.52 | 4.7 |
| Human | Unknown (resistant) | 19.9 | 72.6 | 0.33 | 7.2 |