List of chemicals tested. Chemical names, abbreviations, and applications/targets/mechanisms of the test compounds are summarized.
JCI No | Name | Abbreviation | Application/Target/Mechanism |
|---|---|---|---|
| -691 | Trioctyltin | TOT | Organotin |
| -690 | Triphenyltin | TPT | Organotin |
| -689 | Dibutyltin | Organotin | |
| -688 | AM-580 | RARα | |
| -687 | TTNPB | RAR | |
| -686 | 13-cis Retinoic acid | 13-cis | RAR |
| -607 | Methoprene | Agricultural chemical | |
| -606 | Methoprene acid | RXR | |
| -605 | 5-aza-2′-deoxycytidine | 5-AzaC | Methylation |
| -604 | Carbaryl | Agricultural chemical | |
| -603 | Acephate | Agricultural chemical | |
| -602 | Sodium arsenite | Agricultural chemical | |
| -601 | Testosterone propionate | TP | Testosterone |
| -600 | Ethynyl estradiol | EE | Estrogenic |
| -599 | Thiram | Agricultural chemical | |
| -598 | Dimethylformamide | DMF | Solvent |
| -568 | α-Bungarotoxin | αBuTX | Neurotoxin |
| -567 | Snake venom from Trimeresurus flavoviridis | SV-TF | Snake venom |
| -566 | Snake venom from Crotalus atrox | SV-CA | Snake venom |
| -565 | Snake venom from Agkistrodon halys blomhoffii | SV-AHB | Snake venom |
| -564 | Dexamethasone | DEX | Steroid |
| -563 | 3-Methylcholanthrene | 3-MC | Teratogenicity/carcinogenicity |
| -562 | N-Ethyl-N-nitrosourea | ENU | Teratogenicity/carcinogenicity |
| -561 | Diethylnitrosamine | DEN | Teratogenicity/carcinogenicity |
| -560 | All trans-retinoic acid | ATRA | RAR + RXR |
| -559 | 9-cis Retinoic acid | 9-cis | RAR |
| -558 | Levothyroxine | T4 | Thyroid hormone |
| -557 | 3-Amino-1H-1,2,4-triazole | 3AST | Agricultural chemical |
| -555 | 2-Vinylpyridine | 2VP | Synthetic intermediate |
| -553 | Phenobarbital | PB | Antiepileptic |
| -552 | Acetaminophen | APAP | Analgetic |
| -551 | Isoniazid | Phthisic | |
| -549 | 4-Ethylnitrobenzene | 4ENB | Synthetic intermediate |
| -548 | 1,2-Dichloro-3-nitrobenzene | 1,2DC3NB | Pigment/synthetic intermediate |
| -546 | N-Methylaniline | NMA | Synthetic intermediate |
| -545 | 2-Aminomethylpyridine | 2AMP | Synthetic intermediate |
| -544 | 1H-1,2,4-Triazole | Synthetic intermediate | |
| -543 | 1H-1,2,3-Triazole | Synthetic intermediate | |
| -542 | 4-Amino-2,6-dichlorophenol | 4A2,6DCP | Synthetic intermediate |
| -541 | 2,4-Dinitrophenol | 2,4 DNP | Agricultural chemical |
| -513 | Capsaicin | Food constituent | |
| -485 | 2-Methoxyestradiol | Estrogenic | |
| -466 | Colcemid | Spindle inhibitor | |
| -465 | 2,4-Dinitrochlorobenzene | 2,4DCB | Pigment/mutagenesis |
| -464 | Troglitazone | Diabetic | |
| -463 | Clofibrate | Antilipemic | |
| -459 | Bis(2-ethylhexyl)phthalate | DEHP | Plasticizer |
| -458 | Thiourea | Agricultural chemical | |
| -447 | Cacodylic acid | Agricultural chemical | |
| -446 | Amitrole | Agricultural chemical | |
| -445 | 4-Octylphenol | OP | Reproductive effector |
| -444 | 2,6-Dimethylaniline | 2,6-Xylidene | Natural product |
| -443 | 1,2-Dibromo-3-chloropropane | DBCP | Agricultural chemical |
| -442 | 1,1-Dimethylhydrazine | 1,1DMH | Reproductive effector |
| -441 | Sulfanylamide | Agricultural chemical | |
| -440 | Streptozotocin | Agricultural chemical | |
| -439 | Spironolactone | Aldosterone antagonist | |
| -438 | para-Aminoazobenzene | pAAB | Pigment/mutagenicity/carcinogenicity |
| -437 | para-Cresidine | Pigment/carcinogenicity | |
| -436 | Neostigmine bromide | Parasympathomimetics | |
| -435 | para-Dichlorobenzene | pDCB | Pigment/Agricultural chemical |
| -434 | Phenytoin | Antiepileptic | |
| -433 | ortho-Toluidine | oToluidine | Pigment |
| -432 | Imipramine | Antidepressant | |
| -431 | Cobalt chloride | Teratogenicity/mutagenicity | |
| -428 | Atrazine | Agricultural chemical | |
| -427 | Propylthiouracil | Teratogenicity/carcinogenicity | |
| -426 | Thalidomide (l + d) | Teratogenicity | |
| -425 | Carbon tetrachloride | CCl4 | Teratogenicity/carcinogenicity |
| -424 | Hydroquinone | Oxidative stress | |
| -423 | Monocrotaline | Mutagenicity/carcinogenicity | |
| -422 | Vinyl chloride | Carcinogenicity | |
| -421 | Tributyltin chloride | TBT | Ship bottom paint/organotin |
| -420 | Valproic acid | Antiepileptic | |
| -419 | Benzene | Carcinogenicity | |
| -418 | Acrylamide | Neurotoxin/carcinogenicity | |
| -417 | Hexachlorobenzene | BHC | Agricultural chemical/carcinogenicity |
| -346 | 2-Deoxyglucose | 2-DG | Glycolytic pathway/glycosylation inhibitor |
| -325 | Pentachlorophenol | PCP | Agricultural chemical/teratogenicity/carcinogenicity |
| -324 | Aniline | Oxidative stress/methemoglobinemia/carcinogenicity | |
| -323 | Triazine | Agricultural chemical | |
| -322 | Edifenphos | EDDP | Agricultural chemical/antibiotics/choline esterase |
| -321 | γ-1,2,3,4,5,6-Hexachlorocyclohexane | γ-BHC | Agricultural chemical/carcinogenicity |
| -320 | Dichlorvos | DDVP | Agricultural chemical/teratogenicity/carcinogenicity |
| -319 | O-Ethyl O-4-nitrophenyl phenylphosphonothioate | EPN | Agricultural chemical |
| -318 | Cadmium chloride | CdCl2 | Teratogenicity/carcinogenicity |
| -317 | Phenylmercury acetate | PMA | Fungicides/mutagenicity |
| -316 | Mercaptoacetic acid | Synthetic intermediate | |
| -315 | 1,3-Diphenylguanidine | DPG | Vulcanizing agent |
| -314 | 3,4,4′-Trichlorocarbanilide | TCC | Cosmetics/antibacterial agent |
| -313 | 3-Iodo-2-propynyl butylcarbamate | IPBC | Antibacterial agent |
| -311 | 2,3,3,3-2′,3′,3′,3′-Octachlorodipropylether | S-421 | Agricultural chemical/antibacterial agent |
| -310 | 1,2-Benzisothiazolin-3-one | BIT | Antibacterial agent |
| -309 | Isobornylthiocyanoacetate | IBTA | Antibacterial agent |
| -308 | p-Chlorophenyl-3-iodopropargylformal | CPIP | Antibacterial agent |
| -307 | Zinc butylxanthate | ZBX | Vulcanizing agent |
| -306 | Polypropylene glycol | PG | Synthetic intermediate |
| -305 | 10,10′-Oxy-bis(phenoxyarsine) | OBPA | Antibacterial agent |
| -296 | Snake venom from Naja naja kaouthia | SV-NNK | Snake venom |
| -295 | Snake venom from Naja nigricollis | SV-NN | Snake venom |
| -294 | 2,5-di(tert-butyl)-1,4-Hydroquinone | DTBHQ | Oxidative stress |
| -293 | Ibotenic Acid | Mushroom toxin/neurotoxin | |
| -292 | N-Methy-4-phenyl-1,2,3,6-tetrahydropyridine | MPTP | Neurotoxin |
| -289 | Tetrodotoxin | Natural product/Na+ channel inhibitor | |
| -288 | ICI 182,780 | Estrogen antagonist | |
| -275 | Benzophenone | Agricultural chemical | |
| -274 | 1,2-Dibromo-3-chloropropane | DBCP | Antibacterial agent/insecticide/carcinogenicity |
| -273 | Zineb | Agricultural chemical | |
| -272 | Dieldrin | Insecticide | |
| -271 | Hexachlorobenzene | HCB | Antibacterial agent/carcinogenicity |
| -270 | Ziram | Antibacterial agent/vulcanizing agent | |
| -269 | Chlordane | Insecticide/carcinogenicity | |
| -268 | 4,4′-Dichlorodiphenyltrichloroethane | p,p′-DDT | Insecticide/carcinogenicity/teratogenicity |
| -267 | Bisphenol A | BPA | Estrogenic |
| -266 | 17-β-Estradiol | E2 | Estrogenic |
| -265 | Diethylstilbestrol | DES | Estrogenic |
| -261 | Paraquat | Agricultural chemical/oxidative stress | |
| -247 | Ouabain | Cardiac glycosides | |
| -245 | Okadaic acid | Natural product/PP1, PP2A inhibitor | |
| -242 | Antimycin A1 | Agricultural chemical | |
| -232 | Digoxin | Cardiac glycosides | |
| -201 | OH-Flutamide | Flutamide derivative/androgen antagonist | |
| -200 | Flutamide | Anticancer drugs/androgen antagonist | |
| -185 | 30% H2O2 | Oxidative stress | |
| -182 | N-Acetyl-l-cysteine | NAC | Super oxyside scavenger |
| -181 | l-Ascorbic acid | Food constituent | |
| -179 | Dopamine | Neurotransmitter | |
| -177 | Caffeine | Food constituent | |
| -168 | Cycloheximide | Protein synthesis inhibitor | |
| -144 | 4-Hydroxyphenylretinamide | 4-HPR | RAR |
| -137 | Indomethacin | COX inhibitor | |
| -99 | SN-38 | Irinotecan derivative/Topo I | |
| -96 | Toremifene | Anticancer drugs/estrogen antagonist | |
| -95 | Tamoxifen | Anticancer drugs/estrogen antagonist | |
| -63 | Cyclosporin A | Anticancer drugs/helper T cell | |
| -46 | HCFU | Anticancer drugs/antimetabolite(pyrimidine) | |
| -36 | Docetaxel | Anticancer drugs/tubulin | |
| -35 | Paclitaxel | Anticancer drugs/tubulin | |
| -34 | Colchicine | Antipodagric/tubulin | |
| -33 | Cisplatin | Anticancer drugs/DNA cross linker | |
| -32 | Carboplatin | Anticancer drugs/DNA cross linker | |
| -31 | Irinotecan | Anticancer drugs/Topo I | |
| -30 | Camptothecin | CPT | Anticancer drugs/Topo I |
| -24 | Methotrexate | Anticancer drugs/DHFR | |
| -19 | Vincristine | Anticancer drugs/tubulin | |
| -18 | Vinblastine | Anticancer drugs/tubulin | |
| -16 | Mitomycin-C | MMC | Anticancer drugs/DNA alkylator |
| -9 | Tegafur | Anticancer drugs/antimetabolite(pyrimidine) | |
| -8 | 5-Fluorouracil | 5-FU | Anticancer drugs/antimetabolite(pyrimidine) |
| -5 | Cytarabine | Anticancer drugs/antimetabolite(pyrimidine) | |
| -4 | Nitrogen mustard |
| Anticancer drugs/DNA alkylator |
RAR, retinoic acid receptor; RXR; retinoid X receptor.