TABLE 2

Neither CRIP1a nor CRIP1b altered the time course of Ca2+ current inhibition or the recovery from inhibition by the CB1 agonist WIN 55,212-2 in SCG neurons microinjected with cDNA encoding CB1, CB1 and CRIP1a, or CB1 and CRIP1b


SCG neurons expressing

N

Time to 90% Maximal Inhibition

Time to 50% Recovery
s s
CB1 8 40 ± 4 71 ± 7
CB1 + CRIP1a 14 59 ± 11 87 ± 6
CB1 7 42 ± 6 63 ± 8
CB1 + CRIP1b
6
39 ± 4
82 ± 21