TABLE 1
Effect of SS14 on the internalization of wild-type and mutant sst2A receptors
Values for the EC50 and the extent of internalization for WT and mutant sst2A receptors were determined by nonlinear regression analysis of sigmoidal dose-response curves obtained in three independent experiments similar to that shown in Fig 4, bottom. Values for the half time of internalization were obtained from two to four independent experiments like the experiment shown in Figure 4, top. Data are presented as the mean ± S.E.M. for the EC50 and as the mean ± S.D. for t½.