Relative PPARα mRNA levels in livers of male Sprague-Dawley Rats treated with either DHEA or Nafenopin
Male Sprague-Dawley rats were maintained on AIN-76A diet and injected i.p. daily for 4 days with corn oil or corn oil containing either DHEA or nafenopin to attain a 100 mg/kg dosage. The rats were euthanized with CO2, and livers were removed to prepare mRNA as described under Materials and Methods. The statistical values are relative to control.
Treatment Condition | Relative mRNA Expression | P Value |
|---|---|---|
| Control | 100 ± 1 | |
| DHEA | 594 ± 73 | .005 |
| Nafenopin | 69 ± 8 | .05 |