Effect of IL-13 on KCl- and CCh-induced contractions in isolated murine tracheal rings of p110δD910A and DO11-10 mice
Data are expressed as mean Emax ± S.E.M. for n = 6 pairs of tracheal rings.
| KCl | CCh | |||
|---|---|---|---|---|
| Control | IL-13 | Control | IL-13 | |
| mN/mg tissue | ||||
| DO11-10 control mice | 1.8 ± 0.2 | 2.9 ± 0.2a | 2.5 ± 0.3 | 3.7 ± 0.3a |
| p110βD910A mice | 1.9 ± 0.3 | 1.8 ± 0.4 | 2.8 ± 0.3 | 2.4 ± 0.2 |
↵ a P < 0.01 compared with non-IL-13-treated control mice.