TABLE 3

Comparison of CYP2C9 coding region SNPs in Hispanic and non-Latino white populations

Coordinates are numbered relative to + 1 of the ATG start codon and use contig NT_030059.12, build 36.1 as a reference.

Variant Allelic Frequencies (95% CI)
SNP Position
Site
Nucleotide Change
Effect
Allele Designation
Hispanic (Mexican Descent) (n = 386)
Non-Latino White (n = 384)
3608 Exon 3 430C>T R144C CYP2C9*2 0.070 (0.041, 0.099) 0.110 (0.074, 0.146)
42,614 Exon 7 1075A>C I359L CYP2C9*3 0.044 (0.021, 0.067) 0.060 (0.033, 0.087)
42,615 Exon 7 1076T>C I359T CYP2C9*4 N.O. N.A.
42,619 Exon 7 1080C>G D360E CYP2C9*5 N.O. N.A.
10,601
Exon 5
delA
Frame shift
CYP2C9*6
N.O.
N.A.

  • N.A., not applicable; N.O., not observed.