Inhibitory activity of CBAs against giant cell formation in co-cultures of SIV- or HIV-1-exposed Raji/DC-SIGN cells and uninfected C8166 cells
Values are presented as mean ± S.D. of two to three independent experiments.
CBA | IC50 (Giant Cell Formation) | ||
|---|---|---|---|
| Raji/DC-SIGN/HIV-1 and C8166 Cocultures | Raji/DC-SIGN/SIV and C8166 Cocultures | ||
| μM | |||
| HHA | 0.64 ± 0.15a | 0.032 ± 0.017 | |
| GNA | 0.84 ± 0.05a | 0.046 ± 0.040 | |
| UDA | 3.4 ± 1.1a | 0.38 ± 0.33 | |
| PRM-A | 23 | 19 ± 8.9 | |