Receptor Subtype | No-BAPTA | BAPTA | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ACh | τ | P Value | n | ACh | τ | P Value | n | |||||||
s | s | |||||||||||||
CT-α4β2 | 10.6 ± 3.2 | 1.75 ± 0.25 | 12 | 10.6 ± 3.2 | 7.7 ± 1.4 | 3 | ||||||||
40.5 ± 8.8 | 1.21 ± 0.19 | 12 | 40.5 ± 8.8 | 6.8 ± 1.0 | 3 | |||||||||
767 ± 62 | 1.33 ± 0.16 | 12 | 767 ± 62 | 6.5 ± 0.7 | 3 | |||||||||
α4β2-L301V | 1.6 ± 0.9 | 1.13 ± 0.11 | 0.005 | 9 | 6.7 ± 1.3 | 7.7 ± 0.9 | 1.000 | 3 | ||||||
6.8 ± 4.7 | 0.84 ± 0.07 | 0.058 | 9 | 42.7 ± 10.6 | 7.3 ± 1.2 | 0.767 | 3 | |||||||
1000 ± 0 | 6.30 ± 1.09 | 0.003 | 9 | 341 ± 85 | 14.8 ± 5.1 | 0.247 | 3 | |||||||
α4β2-V308A | 1.3 ± 0.4 | 1.25 ± 0.13 | 0.098 | 12 | 6.6 ± 1.3 | 8.3 ± 1.2 | 0.742 | 3 | ||||||
8.4 ± 2.3 | 1.09 ± 0.11 | 0.706 | 12 | 26.7 ± 5.3 | 11.3 ± 2.8 | 0.025 | 3 | |||||||
| 900 ± 40 | 5.35 ± 1.14 | 0.0001 | 12 | 426 ± 85 | 6.5 ± 1.5 | 1.000 | 3 |