Comparison of activity of β-PEA and d-amphetamine at TAAR1 as measured by column cAMP assay and BRET assay
Values are estimated from experiments presented in Fig. 4, B and C.
| Compounds | Column Assay | BRET Assay | ||
|---|---|---|---|---|
| EC50 | Efficacy (Proportion of β-PEA) | EC50 | Efficacy (Proportion of β-PEA) | |
| M | % | M | % | |
| β-PEA | 5.8 ± 0.58 × 10−7 | 100 | 1.08 ± 0.29 × 10−7 | 100 |
| d-Amphetamine | 9.3 ± 2.79 × 10−7 | 73.9 ± 12.6 | 1.36 ± 0.14 × 10−7 | 62.6 ± 1.7 |