TABLE 2

Deactivation rates from steady-state for mutant GluR6 subunits in response to Dom.


Mutant

τ1

τ1

τ2

n
ms % s
WT 630 ± 70 74 ± 5 2.5 ± 0.2 25
A490M 530 ± 90 54 ± 8 2.1 ± 0.2 5
A490R 980 ± 150 74 ± 4 4.2 ± 0.3 4
V685Q 12.5 ± 1.0 100 17
M691A 735 ± 30 100 2
M691K
190 ± 20
99.6 ± 0.3
1.5 ± 0.2
3
  • Fast (τ1) and slow (τ2) decay exponentials are shown in ms & s respectively, with the contribution of the fast component indicated (%τ1).