Apparent affinity of vesicular neurotransmitter transporters
Substrate | Transporter | Km | References |
|---|---|---|---|
| Glutamate | VGLUT1 | ∼1 mM | Bellocchio et al., 2000 |
| VGLUT2 | ∼1.1-4.7 mM | Bai et al., 2001; Fremeau et al., 2001; Herzog et al., 2001 | |
| VGLUT3 | ∼0.5-1.5 mM | Fremeau et al., 2002; Gras et al., 2002; Schäfer et al., 2002 | |
| GABA | VGAT/VIAAT | ∼1 mM | McIntire et al., 1997 |
| Acetylcholine | VAChT | ∼1 mM | Varoqui et al., 1996; Kim et al., 1999 |
| Serotonin | VMAT1 | 1.56 μM | Erickson et al., 1992 |
| Dopamine | VMAT2 | 0.32 μM | Liu et al., 1992 |