Summary of FFA2 potencies
Data are average IC50/EC50 values ± standard error (S.E.) from four independent experiments.
Ligand | hFFA2 | mFFA2 | ||||
|---|---|---|---|---|---|---|
| cAMP (IC50) | Aequorin (EC50) | cAMP (IC50) | Aequorin (EC50) | |||
| μM | ||||||
| Acetate | 123.8 ± 9.2 | 3032 ± 1083 | 131.0 ± 9.7 | 1153 ± 159.4 | ||
| Propionate | 125.2 ± 9.9 | 2862 ± 988 | 120.2 ± 10.7 | 709.7 ± 99.5 | ||
| Phenylacetamide 1 | 0.70 ± 0.07 | 0.45 ± 0.07 | 0.96 ± 0.07 | 1.27 ± 0.10 | ||
| Phenylacetamide 2 | 0.48 ± 0.04 | 0.44 ± 0.07 | 0.66 ± 0.07 | 0.62 ± 0.06 | ||