Effect of 1-h DMI pretreatment on agonist-stimulated P-CREB
Values are means (± standard errors) from two to four separate experiments with treatments done in triplicate.
Agonist | -Fold Induction | ||||
|---|---|---|---|---|---|
| Vehicle | Agonist | DMI + Agonist | |||
| SKF 82958 (50 μM) | 1.00 (0.092) | 1.86(0.077)** | 1.86(0.123)** | ||
| FPL 64176 (0.5 μM) | 1.00 (0.032) | 1.61(0.081)** | 1.77(0.052)** | ||
| PMA (0.1 μM) | 1.00 (0.031) | 1.92(0.115)** | 1.81(0.145)** | ||
| NMDA (10 μM) | 1.00 (0.044) | 1.86(0.199)** | 1.71(0.066)** | ||
↵** P < 0.01 compared with corresponding vehicle group.