Channel | ShK-170 IC50 | ShK-192 IC50 | |
---|---|---|---|
pM (-fold difference from Kv1.3) | |||
Kv1.3 | 69 ± 5 | 140 ± 19 | |
Kv1.1 | 7000 ± 1000 (101) | 22,000 ± 3000 (157) | |
Kv1.4 | 137,000 ± 3000 (1985) | >100,000 (>700) | |
Kv1.5 | >100,000 (>700) | >100,000 (>700) | |
Kv1.6 | 18,000 ± 3000 (260) | 10,600 ± 1900 (76) | |
Kv3.2 | 20,000 ± 2000 (290) | 4,200 ± 600 (30) | |
KCa3.1 | 115,000 ± 5000 (1666) | >100,000 (>700) | |
Kv11.1 (HERG) | >100,000 (700) | >100,000 (>700) |