Inhibitory effect of MG132 on serum TNF-α and IL-2 challenged with ConA in mice
Values represent mean ± S.D., n = 6 in each group.
Group | TNF-α | IL-2 | |
|---|---|---|---|
| pg/ml | |||
| Control | 39.19 ± 5.85 | 8.63 ± 4.57 | |
| ConA | 595.35 ± 176.39 | 517.83 ± 253.93 | |
| Bicyclol + ConA | 91.56 ± 24.25* | 95.24 ± 35.78* | |
| MG132 + ConA | 76.18 ± 27.44* | 50.71 ± 27.16* | |
| MG132 | 61.08 ± 20.16 | 8.98 ± 4.83 | |
↵* P < 0.01 vs. ConA group.