Blood biochemical parameters of Mate1(+/+) and Mate1(−/−) mice
Each value represents the mean ± S.D. for six mice.
Parameter | +/+ | −/− |
|---|---|---|
| Total protein (g/dl) | 3.9 ± 0.1 | 3.3 ± 0.6 |
| Albumin (g/dl) | 2.0 ± 0.1 | 1.7 ± 0.3 |
| Creatinine (mg/dl) | 0.1 ± 0.0 | 0.3 ± 0.1*** |
| BUN (mg/dl) | 26.1 ± 0.8 | 30.5 ± 1.6*** |
| Uric acid (mg/dl) | 0.6 ± 0.4 | 0.6 ± 0.3 |
| Glucose (mg/dl) | 253 ± 29 | 254 ± 20 |
| Total cholesterol (mg/dl) | 58 ± 3 | 66 ± 11 |
| Triglyceride (mg/dl) | 87 ± 29 | 98 ± 19 |
| HDL (mg/dl) | 46 ± 7 | 47 ± 7 |
| Sodium (mEq/l) | 140 ± 7 | 133 ± 22 |
| Potassium (mEq/l) | 4.0 ± 0.5 | 3.8 ± 0.7 |
| Chloride (mEq/l) | 106 ± 6 | 99 ± 18 |
| Phosphorus (mg/dl) | 7.8 ± 0.6 | 8.3 ± 1.2 |
| Magnesium (mg/dl) | 1.9 ± 0.3 | 2.0 ± 0.2 |
| ALP (U/l) | 486 ± 67 | 466 ± 52 |
| CPK (U/l) | 67 ± 14 | 70 ± 9 |
| AST (U/l) | 33 ± 4 | 36 ± 8 |
| ALT (U/l) | 25 ± 4 | 27 ± 6 |
| γ-GTP (U/l) | 3 ± 1 | 4 ± 1 |
| LAP (U/l) | 39 ± 3 | 40 ± 2 |
| Amylase (U/l) | 2812 ± 645 | 2884 ± 553 |
| LDH (U/l) | 246 ± 72 | 221 ± 24 |
| Total bilirubin (mg/dl) | 0.3 ± 0.1 | 0.3 ± 0.1 |
BUN, blood urea nitrogen; HDL, high-density lipoprotein; ALP, alkaline phosphatase; CPK, creatine kinase; AST, aspartate aminotransferase; ALT, alanine aminotransferase; γ-GTP, γ-glutamyltranspeptidase; LAP, leucine aminopeptidase; LDH, lactate dehydrogenase.
↵*** P < 0.001, significantly different from Mate1(+/+) mice.